Detta är en ”case” studie av ett par i 28-årsålder. Manen bedömdes frisk och innan akupunktur  behandling medicinerades han med E-vitamin och Tribestan för att öka testosteronsekretion eftersom test av sperma innan behandling påvisade för litet antal av mobila spermier. Kvinnan hade diagnostiserad endometrios på äggstockarna bilateralt med ”choklad”-cystor bilateralt och även hon behandlades med hormoner. Innan påbörjad akupunkturbehandling avslutades hormonbehandling hos båda. Paret behandlades med akupunktur på en TCM klinik i Scopje, Macedonien av en läkare specialiserad på akupunktur. Behandling pågick i 3 månader med frekvens 1 gång per vecka i 35-40 min per gång. Punktval som användes hos båda patienter var: HN1 (SiShenCong), LI4 (HeGu), ST36 (ZuSanLi), GB34 (YangLingQuan), SP9 (YinLingQuan), SP6 (SanYinJiao), LR3 (TaiChong), RN13 (ZhongWan), RN7 (QiHai), RN4 (GuanYuan), RN2 (QuGu). ST29 (GuiLai), ST25 (TianShu), GB20 (FengChi), DU14 (DaZhui), BL18 (GanShu), BL19 (DanShu), BL20 (PiShu), BL21 (WeiShu), BL25 (DaChangShu) och BL32 (CiLiao). Efter 7 behandlingar blev kvinna  spontant gravid och cystor var borta i de båda äggstockarna. Egen kommentar: även om det är en ”case” studie, tycker jag att punktval kan tillämpas generellt vid behandling av fertilitet hos andra par med tanke på patofysiologi som ligger till grund för fenomenet.

Artikel sökt via databas PubMed;

Sökord: acupuncture, treatment, fertility.

Referens: Zhu J, Arsovska B, Kozovska K; Acupuncture Treatment for Fertility; Open Access Maced J Med Sci. 2018; 6(9):1685-1687. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182526/

Sammanställd av Dorota Kajhem, grupp 31

Moxibustion can enhance the anti-inflammatory and analgesic effects of conventional medicine in patients with rheumatoid arthritis (RA), Chinese authors report. Their study involved 46 RA patients who were randomly assigned to a control group treated with drug therapy (methotrexate or leflunomide), or a treatment group who received drugs plus moxibustion at ZusanliST-36, ShenshuBL-23 and ashi points. Compared with the control group, the treatment group showed significant improvement in clinical symptoms. Significant differences in levels of pro-inflammatory cytokines (TNF-α and IL-1β) were also found between the groups after eight weeks of treatment, suggesting that moxibustion enhanced the anti-inflammatory effect of drug therapy. Serum biomarkers of angiogenesis (HIF-1α and VEGF) were found to be decreased in the treatment group after therapy, suggesting that moxibustion could also inhibit angiogenesis, a core pathophysiological feature of the inflammation of the synovium which is characteristic of RA. Specific RA-associated serum markers did not show significant differences between the two groups. 

Effect of Moxibustion on HIF-1α and VEGF Levels in Patients with Rheumatoid Arthritis. Pain Res Manag. 2019 Nov 27;2019:4705247

Sammanställd av Amaralis Kuhr, grupp 32

Moxibustion should be considered as an adjunctive therapy to improve lower urinary tract symptoms (LUTS) associated with benign prostate enlargement (BPE). Twenty-nine participants with BPE who were experiencing LUTS were randomly assigned to an integrative group (IG) or a conventional group (CG). The IG received moxibustion (twice weekly for four weeks at Sanyinjiao SP-6, Taichong LIV-3 and Guanyuan REN-4), along with conventional medication for four weeks, followed by conventional medication alone for eight weeks. The CG received conventional medication alone for 12 weeks. Prostate symptom scores were significantly improved in the IG compared with the CG at four weeks after baseline. Incomplete bladder emptying, straining to pass urine and nocturia also showed significant improvements in the IG. Moxibustion as an adjunct for lower urinary tract symptoms associated with benign prostate enlargement: A randomized controlled pilot trial. Medicine (Baltimore). 2020 Jan;99(4):e18918.

Sammanställd av Amaralis Kuhr, grupp 32

Electro-acupuncture outperforms biofeedback therapy for treating chronic neck pain, report Iranian researchers. Fifty patients with chronic neck pain diagnosed as myofascial pain syndrome, characterised by trigger points (TrPs) within taut bands, were randomly assigned to two groups. Patients in the acupuncture group were treated with electro-acupuncture (at points chosen from Jianjing GB-21, Fengchi GB-20, Tianliao SJ-15, Tianzong SI-11, Bingfeng SI-12, Hegu L.I.-14, Quchi L.I.-11, Shousanli L.I.-10, Dazhu DU-14, Baihui DU-20, plus three to four additional TrPs around the painful area), while those in the biofeedback group received visual electromyographic-biofeedback therapy for muscle activity and relaxation. Both groups received the intervention twice a week for a total of six sessions. All patients received instruction in basic rehabilitative exercise and had access to standard analgesic medications. All parameters improved significantly in both groups, however the primary outcome, defined as a 20% reduction in three-month neck pain and dysfunction compared to baseline, was achieved by significantly more patients in the acupuncture group (80%t versus 40%). Additional advantages of acupuncture over biofeedback were observed on measures of pain, neck disability, range of motion and pressure pain threshold at all timepoints from the last treatment session to the end of the three-month follow up period.

Relative Effectiveness of Electroacupuncture and Biofeedback in Treatment of Neck and Upper Back Myofascial Pain: a Randomized Clinical Trial. Arch Phys Med Rehabil. 2020 Jan 16. pii: S0003-9993(20)30004-6

Sammanställd av Amaralis Kuhr, grupp 32

” Therapeutic effects of acupuncture on blood glucose level among patients with type-2 diabetes mellitus: A randomized clinical trial.” Funnen i Journal of Traditional Chinese Medical Sciences. Volume 6, Issue 1, January 2019, Pages 101-107. Verum akupunktur versus sham akupunktur på nivåer av fastande plasma glukos (FPG) och HbA1c bland patienter med typ-2 diabetes mellitus under behandling med metformin. 80 deltagare delades i sham akupunkturgrupp och verum akupunktur grupp. 15 akupunkter, 20 min behandlingstid med jämn manipulation i Verum grupp. Sham grupp behandlades med små nålar, 3 eller 5 mm djup utan manipulation vid icke akupunkturpunkter. 14 sesioner, 10 veckors behandling. Akupunktur i kombination med metformin har större effekt än placebo. Nackdel: studie varade 3 månader, långtidsstudier måste undersökas. Metformin kan ha biverkningar som gastrointestinal irritation, laktatacidos m.m. Vilka effekt har metformin enligt Chinese Medicine? Akupunkterna: Sj5, St25, St36, St40, Ren6, Ren 12, Bl13, Bl20, Bl23, Sp10, Sp6, Liv3, Li4, Li11.

Sammanställd av Begonia Menendez, grupp 32